Hannon-Elledge shRNA Library Standardizes Barcode Technology on Agilent Technologies Microarrays

Gregory Hannon, Ph.D., Howard Hughes Medical Institute investigator at Cold Spring Harbor Laboratory, and Stephen Elledge, Ph.D., pioneers in the construction of short hairpin RNA interference (shRNAi) libraries, have adopted the Agilent Technologies (NYSE: A) microarray platform to read out the individual barcodes present in the libraries and facilitate their screening. The use of the barcode arrays makes it possible, for the first time, for these complex libraries to be used and screened without sophisticated and expensive automation. It represents the democratization of the use of the shRNA libraries, according to Agilent.

Source: Agilent