Scientists at Hokkaido University to Analyze Parkinson’s and Alzheimer’s Disease Pathways using HuCAL-based Antibodies

AbD Serotec, a Division of MorphoSys AG, Munich, announced today the publication of a scientific research paper from a customer using antibodies generated from the MorphoSys HuCAL GOLD antibody library. Using the rapid, high-throughput antibody generation system, a set of monoclonal and fully human mini-antibodies was selected that specifically recognize an oxidized form of the DJ-1 (PARK7) protein. Scientists working in the team of Dr. Hiroyoshi Ariga at Japan’s renowned Hokkaido University subsequently analyzed these antibodies in detail and published the results in the journal Neuroscience Letters. The analysis demonstrates that the HuCAL-based antibody fragments provide a set of useful probes for studying the protein DJ-1 specifically oxidized at a single amino acid. DJ-1 was initially identified by researchers a! t Hokkaido University as a novel cancer target and has recently been linked to certain forms of Parkinson’s and Alzheimer’s disease. AbD Serotec will make the DJ-1 specific antibody available via its sales catalog and customer website.

Source: AbD Serotec